High Throughput Screening: An Overview

High throughput screening (HTS) is a highly valuable experimental process to assaying a large number of parameters against specific criteria.  For drug discovery and development, it provides a systematic and efficient method of identifying potential targets, drugs and/or molecular information that can be beneficial to fighting disesase.  Successful screening is dependent on the type of experimental set-up and the careful implementation of that set-up in a high-throughput platform.  

Although not comprehensive, here are some resources for acclimating to the world of HTS and drug discovery:

Academic Drug Discovery Consortium (TxSACT is a member)
http://addconsortium.org/education-landing.php

National Center for Advancing Translational Sciences, Expertise and Resources
http://www.ncats.nih.gov/expertise

Society for Lab Automation and Screening
http://www.slas.org/resources/information/

Nature Reviews Drug Discovery
http://www.nature.com/nrd/index.html

FDA Critical Path Initiative
http://www.fda.gov/ScienceResearch/SpecialTopics/CriticalPathInitiative/

National Cancer Institute, Research Resources
https://resresources.nci.nih.gov/resources/